O, The Oprah Magazine has a feature on hair loss in women in their March 2010 issue.
Dr. Bernstein was consulted for the article and discussed female hair transplantation.
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Home » Hair Transplant Blog » Hair Follicle
O, The Oprah Magazine has a feature on hair loss in women in their March 2010 issue.
Dr. Bernstein was consulted for the article and discussed female hair transplantation.
Q: I just read a press release saying that researchers have developed a successful technique to clone hair by using a wound healing powder called MatriStem MicroMatrix. Is this new technique really a breakthrough in hair cloning? And if so, when can we start cloning hair?
A: To the best of my knowledge, the claims made for hair cloning in the article are totally unfounded. The “healing powder” MatriStem, although promising for wound healing, has not yet been shown to grow hair.
Q: Why does a hair transplant grow – why doesn’t the transplanted hair fall out?
A: Hair transplants work because hair removed from the permanent zone in the back and sides of the scalp continues to grow when transplanted to the balding area in the front or top of one’s head. The reason is that the genetic predisposition for hair to fall out resides in the hair follicle itself, rather than in the scalp. This predisposition is an inherited sensitivity to the effects of DHT, which causes affected hair to decrease in diameter and in length and eventually disappear – a process called “miniaturization.” When DHT resistant hair from the back of the scalp is transplanted to the top, it will continue to be resistant to DHT in its new location and grow normally.
Q: I heard about the Lgr5 gene being a breakthrough in hair cloning. What’s the latest on that?
A: Many scientists feel that adult stem cells house the answer to cloning (regeneration) of hair follicles. One of the problems of hair cloning, however, is that the cells, once duplicated, “forget” that they are hair follicle cells.
It has recently been discovered that the Lgr5 gene, located in stem cells, appears to contain the “global marker” present in all adult hair follicles. If Lgr5 gene is the “calling card” of the cell, it may carry the cell lineage and shoulder the responsibility of signaling to surrounding stem cells what they are actually supposed to do as they multiply.
Q: How far into the scalp are the grafts placed and is the follicle far enough into the scalp that it will not be damaged? I have heard that the critical time to not touch your scalp is the first 2-3 weeks after the procedure.
A: The growth part of the follicle is 3-4mm into [...]
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