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Hair Restoration Research

Hair Cloning Researchers Outline Hurdles Towards Hair Loss Therapy

Dr. Claire Higgins and her colleague Dr. Colin Jahoda have published an overview of hair cloning and the challenges scientists face in attempting to develop hair regeneration therapies for androgenetic alopecia, or common balding. The article, published in Hair Transplant Forum International, points to two central problems in developing a hair loss therapy. The first is the difficulty in getting dermal papilla cells in humans to self-aggregate and form hair follicles and the second is the inability, thus far, of scientists to generate normal hairs and follicles.

Higgins C, et al. 2014

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Hair Restoration Research

Columbia University Scientist Induces Hair Follicle Growth from Dermal Papilla Implants

We have previously discussed Dr. Angela Christiano’s work on hair loss genetics with her team at Columbia University in New York. A review of the 16th annual meeting of the European Hair Research Society brings to our attention new research being conducted by a scientist who works at Dr. Christiano’s laboratory, Dr. Claire Higgins.

Dr. Higgins is studying the inductive properties of the dermal papilla (DP), which is a group of cells that form the structure directly below each hair follicle.

Higgins C, et al. 2012

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Bernstein Medical In The News

Dr. Bernstein Proposes Improvements to FUE Hair Transplant Procedures

In the latest in a long line of improvements made to hair restoration procedures, Dr. Bernstein has published an article in Hair Transplant Forum International which improves the FUE procedure even further, whether performing follicular unit extraction with the FUE robot or by hand.

In his article, Dr. Bernstein suggests two techniques to enhance the FUE procedure. First, he recommends that surgeons create recipient sites prior to extraction, in order to decrease the time grafts are in their holding solution outside the body. Second, he suggests adding time between site creation and graft harvesting and placement, to allow recipient site healing to progress.

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Hair Restoration Answers

Is Genetic Hair Loss Linked to Other Diseases?

Q: There was a retrospective study by Lotufo et al. linking male pattern baldness to heart disease. Do you think there are other links like this for androgenetic alopecia?

A: Family studies revealed both the androgen receptor locus on the X chromosome, as well as a new locus on chromosome 3q26. Association studies performed in two independent groups revealed a locus on chromosome 20 (not near any known genes) as well as the androgen receptor on the X chromosome. Read on for the rest of the answer.

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Hair Restoration Answers

Can Body Hair Transplant be Negatively Affected by Finasteride?

After trading anecdotes with fellow hair loss physicians about how finasteride can reduce body hair in some patients, Dr. Sharon A. Keene asked whether finasteride might have a negative effect on patients who have body hair transplant (BHT) procedures. While the current research is inconclusive, her review sheds light on how to avoid any possible negative impact that finasteride might have on patients who have body hair transplant procedures.

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Bernstein Medical In The News

Densitometry Makes Cover of Hair Transplant Forum International

Densitometry - Hair Transplant Forum International - March/April 1997The lead article in the March/April 1997 issue of Hair Transplant Forum International focuses on the latest tools available for assessing whether or not a person experiencing hair loss is a good candidate for hair transplant surgery.

Dr. Bernstein uses the techniques of densitometry and video-microscopy to analyze the scalp under high-powered magnification. This gives the doctors vital information for making decisions about whether patients are candidates for hair transplant surgery.

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Bernstein Medical In The News

Dr. Norwood On The Origin of Follicular Transplantation

Follicular Transplantation - Hair Transplant Forum International - July/August 1997Dr. O’tar Norwood discusses the origin of follicular transplantation, and the influence that Dr. Bernstein’s research and publications have had on the evolution of the hair transplant procedure. Read a segment of the article:

The evolution of “follicular transplantation” can be attributed to three people. Dr. Robert Bernstein coined the phrase and advanced the concept. Dr. Bob Limmer introduced the use of the binocular microscope, providing the technology, and Dr. David Seager showed by direct hair counts, comparing the growth of grafts cut with and without the microscope, how the hair growth was improved when the follicular unit was kept intact.

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Bernstein Medical In The News

Dr. Bernstein Featured In FUT Editorial By Influential Hair Transplant Surgeon

The following is a portion of “An Idea Whose Time Has Come,” an editorial written by O’Tar T. Norwood, MD — founder of the Norwood Classification System for Hair Loss — and published in the May/June 1997 issue of “Hair Transplant Forum International”:

An Idea Whose Time Has Come - O'tar NorwoodI just returned from visiting Dr. Bob Bernstein in New York, and was impressed with his operation and even more impressed with his thoughts, observations, and insights into hair transplant surgery. He applies scientific methods to his work, is academically honest, and has an almost eerie instinctive knowledge of hair transplant surgery. Of course he has Dr. Bill Rassman to work with, but it is still remarkable. Dr. Bernstein is best known for introducing follicular transplantation to hair transplant surgery, an idea Bob Limmer has been pushing for ten years with the use of the binocular microscope, but no one would listen to him. Dr. Limmer, however, never used the term follicular transplantation. Using the microscope, you automatically dissect the follicular units. It can’t be avoided if done properly.

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