Propecia® (finasteride 1mg) is an oral medication, manufactured by Merck Pharmaceuticals, that blocks the conversion of testosterone to dihydrotestosterone (DHT), the hormone largely responsible for male pattern baldness. It does this by inhibiting the action of the type II 5-alpha reductase enzyme that is present in higher concentration in and around the hair follicles of […]
Answers to frequently asked questions about Bernstein Medical - Center for Hair Restoration, our hair loss consultations, and hair restoration procedures
Throughout history, hair has been an important symbol of gender, social, religious and professional status. The significance of hair is as great as that of clothing, jewelry, tattoos, weapons, and crowns. The importance of hair goes back at least as far as the Stone Age. In 1991, a man’s body was found frozen in a […]
The principle behind hair transplantation is quite simple. The hair that grows on the back and sides the scalp tends to be permanent in most individuals. It persists even in advanced degrees of androgenetic hair loss because follicles in these locations are not subject to the affects of the hormone dihydrotestosterone (DHT). The resistance or […]
Bernstein Medical New York Center for Hair Restoration 110 East 55th Street, 11th Floor New York, NY 10022 212-826-2400 Contact Us Directions Bernstein Medical – Center for Hair Restoration welcomes men and women from California who are seeking the best hair restoration treatments available today. Dr. Robert M. Bernstein — a world-renowned hair restoration physician […]
Hair Transplants in Young Patients Surgical hair restoration is generally not advised for patients younger than 25 with androgenetic alopecia (male pattern baldness) for these reasons: In a young person, one cannot tell if the donor area will be stable over time. If the donor area is not stable, then there may not be enough permanent hair to transplant. The earlier one’s hair loss begins, the more extensive it will likely become. With extensive hair loss, the demand for hair may exceed the donor supply and, therefore, the coverage that would be possible with a hair transplant would not be enough to satisfy a young person (whose goal is generally a full head of hair and a low hairline).
Featured Press 11 Shampoos That’ll Make Thin Hair Feel Stronger and Fuller January 21, 2025 Hair shedding and hair loss aren’t the same October 28, 2024 The 13 Best Hair Growth Serums for Long, Strong Hair October 6, 2024 We know a lot less about hair loss in women than in men. Here’s why. September […]
In the study, 416 men with male pattern hair loss (MPHL) ages 21 to 45 years old, were randomized to receive dutasteride 0.05, 0.1, 0.5 or 2.5 mg, finasteride 5 mg, or placebo daily for 24 weeks. The results of the study showed that dutasteride increased hair counts in a dose-dependent fashion and dutasteride 2.5 mg was superior to finasteride 5mg at 12 and 24 weeks. [...] Concerning possible sexual adverse events, there was no evidence in the present study that either dutasteride or finasteride was associated with impotence. However, 9 men in the 2.5-mg dutasteride group complained of decreased libido, compared with 1 man in the 0.5-mg dutasteride group and 3 men in the finasteride group. As with previous studies with finasteride, this adverse event was characterized as either mild or moderate in severity and often resolved with a continuation of the medication. In the 4-year follow-up of the phase III trials in BPH, dutasteride (0.5 mg) was well tolerated and the incidence of the most common sexual adverse events was low and tended to decrease over time.
We all have seen that some bald sons have bald fathers, even when no one on the mother’s side of the family has any hair loss. This suggests that the genetics of male pattern alopecia is more complicated, with multiple genes influencing hair growth. And it is likely that the inheritance of baldness is polygenetic, with relevant genes coming from both the x-chromosome of the mother and non-sex chromosomes of either parent. So where are the other genes? Two independent research groups, one from England and the other Germany, both published in the journal Nature Genetics, have identified a gene locus p11 on chromosome 20 that seems to be correlated with male pattern hair loss, and since the gene is on a non-sex chromosome, it offers an explanation for why the inheritance of common baldness can be from either side of the family.
The 2011 study published by a research team led by Dr. Alfredo Rossi, is the first comprehensive investigation on long-term safety and efficacy of finasteride 1mg (Propecia).