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Bernstein Medical - Center for Hair Restoration
Hair Restoration Research

Japanese Researchers Bioengineer Hair Follicles from Stem Cells, Dermal Papillae

Japanese researchers have demonstrated that scientists can bioengineer viable, hair-producing follicles from epithelial stem cells and dermal papilla cells. Using these components, the team produced follicles that exhibit both the normal hair cycle and piloerection (the reflex contraction of a tiny muscle in the hair follicles which creates what is commonly referred to as “goose bumps”). The bioengineered follicles also developed the normal structures found within follicles and formed natural connections with skin tissues, muscle cells, and nerve cells.

Toyoshima K, et al. 2012

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