Learn more about our revised in-office safety policies in response to the COVID-19 pandemic.

212-826-2400
Flagship Office: 110 East 55th Street, New York, NY
Bernstein Medical - Center for Hair Restoration
Hair Restoration Research

Columbia University Study on 3-D Cultures is ‘Substantial Step Forward’ Towards Cloning Human Hair

For four decades, scientists have known about the possibility of using cells derived from the base of hair follicles (dermal papilla cells) to stimulate the growth of new hair. More recently, researchers have been able to harvest dermal papillae, multiply them, and induce the creation of new hair follicles – but only in rats. Now, for the first time, scientists at Columbia University have shown that they can induce new human hair growth from cloned human papillae. This procedure, called “hair follicle neogenesis,” has the potential to solve one of the primary limitations in today’s surgical hair restoration techniques; namely, the patient’s finite donor hair supply that is available for transplantation.

A significant number of hair loss patients do not have enough donor hair to be candidates for a hair transplant procedure with the percentage of women lacking stable donor hair greater than in men. This technique would enable both men and women with limited donor reserves to benefit from hair transplant procedures and enable current candidates to achieve even better results.

According to co-study leader Angela M. Christiano, Ph.D., of Columbia University in New York, the ground-breaking publication is a “substantial step forward” in hair follicle neogenesis. While the technology still needs further development to be clinically useful, the implications of successfully inducing new hair follicles to grow from cloned hair cells could be a game-changer in the arena of hair restoration. Instead of moving hair follicles from the donor area to the recipient area, as in a hair transplant, follicular neogenesis involves the creation of new follicles, literally adding more follicles to the scalp rather than merely transplanting them from one part of the scalp to another.

Higgins C, et al. 2013

Posted by Updated
Hair Restoration Research

Research Points To Vitamin D Receptors As Possible Clue To Reversing Hair Loss

Could it be that Vitamin D is the cure for baldness that scientists have been looking for all these years? New research on Vitamin D, and its receptors in hair follicles, has taken us down a previously untrodden path that could, potentially, lead to new medical treatments for hair loss.

The Vitamin D receptor was previously known to stimulate hair follicles, which were in the dormant phase of hair growth, to grow hair when activated. The research into Vitamin D and its effect on hair and skin, centers around this receptor.

Posted by Updated
Hair Restoration Research

Follicular Unit Hair Multiplication with FUE

Follicular unit extraction is a technique of removing one follicular unit at a time from the donor region. The most important limitation of this hair transplant procedure is a high transection rate during the extraction process. In this clinical study, the authors transplanted different parts of transected hair follicle when harvesting with the Follicular Unit Extraction (FUE) technique. Five male patients participated in the study.

In each patient, three boxes of 1 cm2 were marked at both donor and recipient sites. The proximal one-third, one-half, and two-thirds of 15 hair follicles are extracted from each defined box and transplanted in recipient boxes. The density is determined at 12 months after the procedure.

The authors concluded that the survival rate of the transected hair follicles was directly related to the level of transection. The authors demonstrated that even though some of the transected parts of the follicles can survive after being transplanted to the recipient site, the growth rate is not satisfactory and the hair is thinner than the original follicles. As a result of this study, the researchers recommend that the hair transplant surgeon does not transplant the sectioned parts and that they should be careful with the patients whose transection rate is high during Follicular Unit Extraction procedures.

Posted by Updated



Browse Hair Restoration Answers by topic:








212-826-2400