Bernstein Medical - Center for Hair Restoration - Dermatology
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Columbia University Medical Center Education BuildingColumbia University Medical Center Education Building; Courtesy of Diller Scofidio + Renfro and Columbia Medical Center

Dr. Bernstein has a long affiliation with New York-Presbyterian Hospital, the teaching arm of Columbia University’s College of Physicians and Surgeons. In U.S. News & World Report’s 2016-17 survey of America’s best hospitals, New York-Presbyterian was rated #1 in New York and #6 overall in the country.

From a pool of almost 5,000 hospitals, New York-Presbyterian was ranked in the top 50 hospitals for an impressive 15 out of the 16 specialties evaluated by U.S. News, including top five rankings in six of the specialties. It also ranked among the best for 10 children’s specialties and received the highest rating possible for eight different procedures or conditions. U.S. News based the scores on factors such as patient outcomes and patient safety. This is the 16th consecutive year the hospital was rated #1 in New York.

Dr. Bernstein has been working at New York-Presbyterian since his first hospital appointment as a young physician fresh out of postdoctoral training in 1982. In 1990, he graduated to Associate Dermatologist after eight years as an Assistant Dermatologist at the prestigious hospital. In 1996, he was elevated to Assistant Attending for the hospital’s dermatology service. Four years later, in 2000, he was named Associate Attending of the dermatology service, and he has been serving the hospital in that capacity ever since. He has also lectured there on hair transplant surgery.

In 1982, Dr. Bernstein’s first academic appointment at the College of Physicians and Surgeons, Columbia University was Assistant in Clinical Dermatology. After three years he was promoted to Instructor and then five years later to Associate in Clinical Dermatology. From 1995 to 2000 he acted as Assistant Clinical Professor, then from 2000 to 2007 Associate Clinical Professor. In 2007 he was promoted to Clinical Professor of Dermatology at Columbia University, and he has served in that capacity for the past nine years.

Read more about Dr. Bernstein’s hospital and academic appointments in his CV

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Dr. Bernstein summarizes an article in the Journal of the National Cancer Institute:

Curis, Inc., a drug development company, has published data showing the effectiveness of a proprietary Hedgehog pathway activator to stimulate hair growth in adult mice. The study shows that a topically applied small molecule agonist of the Hedgehog signaling pathway can stimulate hair follicles to pass from the resting stage to the growth stage of the hair cycle. The Hedgehog agonist produces no other noticeable short or long-term changes in the skin of the mice.

This study also demonstrated that the Hedgehog agonist is active in human scalp in vitro as measured by Hedgehog pathway gene expression. The results suggest that topical application of a Hedgehog agonist could be effective in treating hair loss conditions, including male and female pattern genetic hair loss.

Preliminary results were presented at the American Academy of Dermatology (AAD) in February 2005. This work was based on a study in 2001 by Sato et. Al. who showed that the Sonic hedgehog gene is involved in the initiation of hair growth in mice.

Reference: Sato N., Leopold PL, Crystal, RG. Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia. Journal of the National Cancer Institute, 2001, Vol. 93, No. 24.

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