Summary of “Hair Regrowth Following a Wnt- and Follistatin-Containing Treatment: Safety and Efficacy in a First-in-man Phase 1 Clinical Trial,” which was originally published in the November 2011 issue of the Journal of Drugs in Dermatology (Volume 10, Issue 11).

Researchers were aware of the importance of follistatin, a binding protein; Wnt 7a, a signaling protein; and wound healing factors on hair growth. In this study, researchers tested the safety and efficacy of an injection of a mixture of naturally-derived molecules on hair growth.

The mixture, called the Hair Stimulating Complex (HSC), contained follistatin, as well as keratinocyte growth factor (KGF), and vascular endothelial growth factor (VEGF). The mixture also showed activity similar to the Wnt signaling protein.

The 26 subjects, each suffering from androgenetic alopecia or common baldness, were given an injection of the mixture. The researchers found that there were no adverse events upon injection. Biopsies taken at 22 and 52 weeks showed no abnormal morphology at the injection site.

The sites were also studied at 12 weeks and 52 weeks to determine the effects of the HSC injection in a bald area on the scalp. At 12 weeks after the injection, hair shafts had increased in thickness by 6.3% and terminal hair density increased 20.6%. At 52 weeks, there was a statistically significant increase in total hair count.

Results of the study suggest that injection of the HSC mixture improved hair growth in people with androgenetic alopecia and that previous research with Wnts, follistatin, and growth factors associated with wound healing and regeneration has been substantiated.

Read the latest in hair cloning research


Share this Page





Robotic FUE Hair Transplants
We perform all FUE procedures using the ARTAS Robot.

Read more
Physician Consults
Meet with our board certified doctors to diagnose your hair loss and discuss treatments.

Schedule a Consult
Hair Transplant Photos
Before & after photos of more than 200 of our patients.

Dr. Bernstein answers common questions about hair restoration.

Video & Audio
Dr. Bernstein's television appearances and Q&A on hair restoration.

Video & Audio
Reasons to Visit
Reasons to visit our hair restoration facility in NYC.

Read more
Hair Loss For Dummies
The layman's guide to hair restoration, FUE, medical treatments, and more.

Read more
Get the latest news and updates in hair restoration from Bernstein Medical.

Sign Up Newsletter Archive
Dr. Bernstein on The Oprah Winfrey Show
Dr. Bernstein explains hair restoration procedures to Oprah and Dr. Oz and shows them a patient’s results.

Watch the Video
Share the Bernstein Medical website with your friends.

Share




© 2005-2016 Bernstein Medical, P.C. All Rights Reserved.

ARTAS, ARTAS Hair Studio, and RESTORATION ROBOTICS logo are among the trademarks and/or registered trademarks of Restoration Robotics, Inc. in the United States and/or other countries.