Summary: Hair Follicle Regeneration in Adult Mouse Skin After Wounding

May 19th, 2007

Dr. Bernstein summarizes an article on stem cells that was published in the journal Nature:

This study demonstrates that after wounding the skin of an adult mouse, an embryonic-like change in the epidermal cells outside of the hair follicle stem cells can be induced to form new hair follicle stem cells. In other words, these cells originate from epidermal skin cells in the wound, but then are able take on the characteristics of hair follicle stem cells and actually produce hair. These regenerated hair follicles establish a stem cell population that can produce a hair shaft and continue through all stages of the follicular cycle. The research suggests that these regenerated hair follicles grow new hair through the introduction of Wnt proteins.

The technology, developed at the University of Pennsylvania School of Medicine, has been licensed by Follica Inc. a privately held medical device company.

Reference: “Hair Follicle Regeneration in Adult Mouse Skin After Wounding,” Ito, M., et al. Nature 447, 316-320, May 17, 2007




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Posted by Robert M. Bernstein M.D. on May 19th, 2007 at 4:35 pm







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