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Platelet Rich Plasma (PRP) for Hair Transplant Procedures

What is PRP?

Human blood is comprised of red blood cells (RBC), white blood cells (WBC), platelets, and plasma. Red blood cells carry oxygen and white cells mediate our inflammatory response and protect us from harmful organisms. By initiating the first step of coagulation, platelets are the key to the body's ability to heal wounds.

It is thought that by increasing the platelet count in a wounded area, the body's healing to that area would be accelerated - explaining the use of platelet rich plasma (PRP) in wound healing.

Platelet rich plasma is concentrated blood plasma which contains approximately five times the number of platelets found in normal circulating blood. In addition, blood plasma contains the growth factors PDGF and VEGF and other bioactive proteins that aid in wound healing.

Uses of PRP

PRP is used in many areas of medicine, including the acceleration of healing of tendon injuries, the treatment of osteoarthritis, in some aspects of dental work (i.e. jaw reconstruction), and in cardiovascular medicine.

Since the concentrated form of plasma has been shown to accelerate wound healing and tissue repair, it is felt that it could potentially benefit hair restoration procedures as well.

To obtain PRP, a patient's blood is spun in a centrifuge that separates the solid from liquid components. This separated "solid" portion of the blood is PRP (platelet rich plasma). PRP is then placed into a syringe and reintroduced into the surgical site.

In hair transplantation, PRP can be injected into the recipient site area to theoretically stimulate the healing of the transplanted grafts and into the donor area to facilitate healing of the donor incision.

Mechanism of Action in Hair Transplants

Hair follicles survive through the absorption of oxygen from surrounding tissue. It is conjectured that the introduction of platelets and white blood cells through platelet rich plasma (PRP) would amplify the body's naturally occurring wound healing mechanism. Others propose that PRP can actually stimulate the stem cells (dermal papilla) of the newly transplanted hair follicles. Some researchers also claim that PRP can be used to stimulate the growth of follicles, thereby reversing hair miniaturization seen in androgenetic alopecia and even preventing hair loss.

While there is much conjecture as to the benefits of using PRP during hair transplantation and its use in the medical treatment of hair loss, there is little scientific evidence to support these theories at the present time. This is an exciting new area in the field of hair restoration that awaits further scientific data.

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