Posts in Topic: Genetics

Is Genetic Test for Hair Loss Worthwhile?

October 14th, 2009

Q: Is it worth getting the genetic test for balding?

A: You’re referring to Hair DX (hairdx.com), which costs about $150 and came to market in January of 2008 as the first test for androgenetic alopecia, aka male pattern baldness.

The test screens for variations in the androgen receptor gene on the X chromosome, the gene that is associated with male pattern hair loss. The purpose of the test is to identify persons at increased risk of developing hair loss before it is clinically apparent – so that medical intervention can be started early, when it is most effective.

It is important to realize that, at this point, there is just an association with this gene and hair loss; the cause and effect has not been proven and the association is not anywhere near 100%. A danger is that patients may overreact to the relatively incomplete information that the test provides. It is best to have the test performed under a doctor’s supervision, so that it can be put in the context of other information that the physician gleans through a careful history, physical and a densitometry hair evaluation. As of this posting, genetic testing for hair loss is not permitted in New York State.


Posted by Robert M. Bernstein M.D. at 7:30 am

Do Genes Cause Male Pattern Baldness and if so Which Ones?

October 28th, 2008

Q: What are the genes that cause male pattern baldness?

A: At this time the genes that actually cause hair loss are still unknown.

However, there are two gene loci, recently identified, that appear to be associated with common baldness. The first is on the Androgen Receptor (AR) gene carried on the x-chromosome and the second is a non-sex chromosome 20p11.


Posted by Robert M. Bernstein M.D. at 11:10 am

Is Hair Loss Hereditary and are Genes Inherited from Mother’s Side or Father’s Side of Family?

July 24th, 2006

Q: Why do some people have a full head of hair into their seventies or eighties and others start to go bald in their late teens or early twenties?

A: The cause is genetic and this poly-genetic trait can be inherited from the mother’s side, the father’s side, or both.

There is an old wives’ tale that it is inherited only from the mother’s parents. Although the inheritance can come from either side, it is actually greater from the mother’s side – but only slightly.


Posted by Robert M. Bernstein M.D. at 8:23 am






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