Posts Tagged: Finasteride

Is Hair Transplant to Recreate Dense Hairline Too Good to be True?

April 28th, 2009

Q: It’s a question that greatly concerns me because I’m investigating getting a transplant sometime next year. I’m 28 and thought I started balding at 26, but photographic evidence suggests it had started somewhere around age 24. I’m roughly a Class 2 now, and thanks to finasteride, I’ve stayed almost exactly where I was at 26 with some improvement (not really cosmetically significant though). However, I am convinced I have some crown and top of the scalp thinning too, but not to a visible degree.

These people getting these miraculous jobs from Canada – it is a trick, right? They can’t honestly expect to be able to get away with what they’ve done over the course of their entire lives, can they?

A: I think you have better insights into hair loss than many hair transplant surgeons. ABI was the “rare” patient who seems to be a stable Class 3. I made that judgment due to: almost no miniaturization at the border of his Class 3 recession, no crown miniaturization, and his unusual family history. He had several older family members who stayed at Class 3 their whole lives.

Since we only have about 6,000 movable follicular units on average in our donor area, placing 3,000 at the hairline is obviously a joke and/or the doctor is playing “Russian Roulette” with the patient’s future.

As you point out, in most patients the hair loss will progress and the person will be out of luck. It is similar to the way flap patients were stuck without additional donor hair as their hair loss progressed. An additional problem was that the flaps were low on the forehead and very dense. The situation is analogous to placing 100 grafts per sq cm2 to create a low, broad hairline in a young person.

If you do the math you can see how ridiculous this tactic is. A person’s original density is only 90-100 follicular units cm2. Patient with Class 6 hair loss lose hair over an area of about 300 cm2.

This consists of:

  • 50cm2 in the front (including a 15cm2 hairline)
  • 150 cm2 for the mid-scalp
  • 100 cm2 for the crown

Therefore, 6000 FUs transplanted to this area = 6000/300 = 20 FU per cm2. This is the number we often work with. We put up to 50cm2 at the very most in the mid-frontal forelock area and then proportionately less in other areas.

However, if you put 3,000 FUs at the hairline, in a density of 100/cm2, then you have covered only 30cm. This leaves only 3,000 FUs for the remaining 270cm2 of balding scalp for a density of a little over 11 FU/cm2.

Now, transplanting 11FU cm2 over the back part of the scalp is not a disaster EXCEPT if the front was transplanted at 100 per cm2. In this situation (as you have accurately pointed out) the patient will look very, very front heavy, with an aggressively placed, dense, broad, hairline and little hair to support it towards the back.

The gamble is that the patient’s baldness doesn’t progress, that finasteride or dutasteride can halt the process if it does progress, or that hair cloning methods will be available to save the day.

In my opinion, elective surgery should not be performed when its success depends upon these uncertainties – and particularly since a cosmetically disfiguring hair transplant can be so debilitating (and avoidable).

The reality is that doctors who claim to perform these procedures may not even be performing follicular unit transplantation. In FUT, the surgeon transplants naturally occurring intact FUs of 1-4 hairs. The extreme dense packing techniques preclude the use of 4- and sometimes even 3-hair grafts. What happens is that the larger FU are spit up. This doubles the graft counts (and the cost to the patient) without giving the patient any more hair. It also increases the risk of follicular damage and poor growth.

Patients in whom 10,000 follicular units are available to transplant are very rare and when they are shown on the internet, should be viewed as the exception rather than the rule.


Posted by Robert M. Bernstein M.D. at 6:05 am

Will Propecia Work Better if Taken at Night or with Food?

April 19th, 2009

Q: What time should I take the Propecia? Does it work better if I take it at night as opposed to the morning and should I take it with meals?

A: It doesn’t matter what time of day you take Propecia and the time can very each day.

The absorption of Propecia (finasteride) is not affected by food, so it can be taken without regard to meals.


Posted by Robert M. Bernstein M.D. at 6:11 am

What Hair Loss Treatment Can Prevent Hairline Retreat, Thinning?

January 20th, 2009

Q: I am having hair thinning and retreating from the front part of the scalp. According to Norwood’s classification I rank a category III. From what I see on the Rogaine pack it is used in hereditary hair loss on the (vertex) on top of the scalp. Any recommendations?

A: Minoxidil does work on the front of the scalp to prevent the progression of hair loss and may thicken areas of early thinning, although it won’t re-grow hair in areas that are bald.

I would also consider using finasteride (the active ingredient in the hair loss medication Propecia) as this will also work on the front of the scalp to prevent further hair loss and to increase areas of thinning – and it is more effective than minoxidil.


Posted by Robert M. Bernstein M.D. at 4:34 am

After Hair Transplant Should One Continue Treatment with Propecia?

January 18th, 2009

Q: If I get transplants, do I still have to continue taking Propecia?

A: Yes, you should.

You do not need finasteride (Propecia) for the hair transplant to work, or the transplanted hair to continue to grow, but finasteride can decrease further hair loss.


Posted by Robert M. Bernstein M.D. at 4:29 am

After Hair Transplant Can One Replace Hair Loss Medication with Laser Therapy, Herbs?

September 15th, 2008

Q: I am interested in a hair transplant, but am turned off by the apparent side effects of follow up Propecia. Could herbs serve the purpose of Propecia? Regarding laser treatments, do they work on their own, or do you need drugs to supplement? Can laser damage in some cases, rather than benefit? It seems odd that laser therapy has been undertaken in Europe for 10 years, yet there are no published studies on the results. Might this be because it doesn’t work in the longer term?

A: Finasteride is the best medication. Herbs are not particularly effective for hair loss. You should consider trying finasteride.

If you are in the 2% group that has side effects with Propecia, just stop taking the medication. If you do not experience side effects, then there is no problem taking the medication long-term. Hair transplant surgery doesn’t prevent the progression of hair loss. That is why it is used in conjunction with medication.

Laser therapy can cause shedding initially (as can Propecia and Rogaine), but this means it is working. It does not cause actual hair loss. Your skepticism of the value of Laser therapy long term is one we have as well. Keep in mind, however, that while long-term studies are extremely important, they are very hard and costly to run and there is little incentive for companies to do this.

It is interesting that the FDA does not require longer term data on medications or devices that need to be used on a continued basis.


Posted by Robert M. Bernstein M.D. at 7:00 am



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