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	<title>Bernstein Medical - Center for Hair Restoration &#187; Dutasteride</title>
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	<link>http://www.bernsteinmedical.com</link>
	<description>Hair Transplant, Hair Restoration &#38; Repair</description>
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		<title>Is Hair Transplant to Recreate Dense Hairline Too Good to be True?</title>
		<link>http://www.bernsteinmedical.com/hairtransplantblog/hair-transplant-too-good-to-be-true/</link>
		<comments>http://www.bernsteinmedical.com/hairtransplantblog/hair-transplant-too-good-to-be-true/#comments</comments>
		<pubDate>Tue, 28 Apr 2009 06:05:22 +0000</pubDate>
		<dc:creator>Robert M. Bernstein M.D.</dc:creator>
				<category><![CDATA[Hairline]]></category>
		<category><![CDATA[Dense Packing of Grafts]]></category>
		<category><![CDATA[Donor Area]]></category>
		<category><![CDATA[Donor Hair Density]]></category>
		<category><![CDATA[Dutasteride]]></category>
		<category><![CDATA[Finasteride]]></category>
		<category><![CDATA[Follicular Unit Transplant]]></category>
		<category><![CDATA[Follicular Units per Square Centimeter]]></category>
		<category><![CDATA[FUT]]></category>
		<category><![CDATA[Mid-frontal Forelock Area]]></category>
		<category><![CDATA[Miniaturization]]></category>
		<category><![CDATA[Norwood Class 2 Hair Loss]]></category>
		<category><![CDATA[Norwood Class 3 Hair Loss]]></category>
		<category><![CDATA[Norwood Class 6 Hair Loss]]></category>
		<category><![CDATA[Norwood Hair Loss Classification]]></category>
		<category><![CDATA[Number of Grafts Per Hair Transplant]]></category>

		<guid isPermaLink="false">http://www.bernsteinmedical.com/dev/newblog/298/hair-transplant-too-good-to-be-true/</guid>
		<description><![CDATA[Q: It&#8217;s a question that greatly concerns me because I&#8217;m investigating getting a transplant sometime next year.  I&#8217;m 28 and thought I started balding at 26, but photographic evidence suggests it had started somewhere around age 24. I&#8217;m roughly a Class 2 now, and thanks to finasteride, I&#8217;ve stayed almost exactly where I was [...]]]></description>
			<content:encoded><![CDATA[<p><strong>Q:</strong> It&#8217;s a question that greatly concerns me because I&#8217;m investigating getting a transplant sometime next year.  I&#8217;m 28 and thought I started balding at 26, but photographic evidence suggests it had started somewhere around age 24. I&#8217;m roughly a Class 2 now, and thanks to finasteride, I&#8217;ve stayed almost exactly where I was at 26 with some improvement (not really cosmetically significant though).  However, I am convinced I have some crown and top of the scalp thinning too, but not to a visible degree.</p>
<p>These people getting these miraculous jobs from Canada &#8211; it is a trick, right?  They can&#8217;t honestly expect to be able to get away with what they&#8217;ve done over the course of their entire lives, can they?</p>
<p><strong>A:</strong> I think you have better insights into hair loss than many hair transplant surgeons. ABI was the &#8220;rare&#8221; patient who seems to be a stable Class 3. I made that judgment due to: almost no miniaturization at the border of his Class 3 recession, no crown miniaturization, and his unusual family history. He had several older family members who stayed at Class 3 their whole lives.</p>
<p>Since we only have about 6,000 movable follicular units on average in our donor area, placing 3,000 at the hairline is obviously a joke and/or the doctor is playing &#8220;Russian Roulette&#8221; with the patient&#8217;s future.</p>
<p>As you point out, in most patients the hair loss will progress and the person will be out of luck. It is similar to the way flap patients were stuck without additional donor hair as their hair loss progressed. An additional problem was that the flaps were low on the forehead and very dense. The situation is analogous to placing 100 grafts per sq cm2 to create a low, broad hairline in a young person.</p>
<p>If you do the math you can see how ridiculous this tactic is. A person&#8217;s original density is only 90-100 follicular units cm2.  Patient with Class 6 hair loss lose hair over an area of about 300 cm2.</p>
<p>This consists of:</p>
<ul>
<li>50cm2 in the front (including a 15cm2 hairline)</li>
<li>150 cm2 for the mid-scalp</li>
<li>100 cm2 for the crown</li>
</ul>
<p>Therefore, 6000 FUs transplanted to this area = 6000/300 = 20 FU per cm2. This is the number we often work with. We put up to 50cm2 at the very most in the mid-frontal forelock area and then proportionately less in other areas.</p>
<p>However, if you put 3,000 FUs at the hairline, in a density of 100/cm2, then you have covered only 30cm. This leaves only 3,000 FUs for the remaining 270cm2 of balding scalp for a density of a little over 11 FU/cm2.</p>
<p>Now, transplanting 11FU cm2 over the back part of the scalp is not a disaster EXCEPT if the front was transplanted at 100 per cm2. In this situation (as you have accurately pointed out) the patient will look very, very front heavy, with an aggressively placed, dense, broad, hairline and little hair to support it towards the back.</p>
<p>The gamble is that the patient&#8217;s baldness doesn&#8217;t progress, that finasteride or dutasteride can halt the process if it does progress, or that hair cloning methods will be available to save the day.</p>
<p>In my opinion, elective surgery should not be performed when its success depends upon these uncertainties – and particularly since a cosmetically disfiguring hair transplant can be so debilitating (and avoidable).</p>
<p>The reality is that doctors who claim to perform these procedures may not even be performing follicular unit transplantation. In FUT, the surgeon transplants naturally occurring intact FUs of 1-4 hairs. The extreme dense packing techniques preclude the use of 4- and sometimes even 3-hair grafts. What happens is that the larger FU are spit up. This doubles the graft counts (and the cost to the patient) without giving the patient any more hair. It also increases the risk of follicular damage and poor growth.</p>
<p>Patients in whom 10,000 follicular units are available to transplant are very rare and when they are shown on the internet, should be viewed as the exception rather than the rule.</p>
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		</item>
		<item>
		<title>What Hair Loss Medications are Effective DHT Blockers and are they Sold Over the Counter?</title>
		<link>http://www.bernsteinmedical.com/hairtransplantblog/dht-blockers/</link>
		<comments>http://www.bernsteinmedical.com/hairtransplantblog/dht-blockers/#comments</comments>
		<pubDate>Mon, 21 Apr 2008 06:49:00 +0000</pubDate>
		<dc:creator>Robert M. Bernstein M.D.</dc:creator>
				<category><![CDATA[Drugs (Medications)]]></category>
		<category><![CDATA[Avodart]]></category>
		<category><![CDATA[DHT]]></category>
		<category><![CDATA[DHT Blockers]]></category>
		<category><![CDATA[Dutasteride]]></category>
		<category><![CDATA[Finasteride]]></category>
		<category><![CDATA[Hair Loss Medication]]></category>
		<category><![CDATA[Hair Loss Medication Over the Counter]]></category>
		<category><![CDATA[Nizoral]]></category>
		<category><![CDATA[Propecia]]></category>
		<category><![CDATA[Proscar]]></category>
		<category><![CDATA[Seborrhea]]></category>

		<guid isPermaLink="false">http://www.bernsteinmedical.com/dev/newblog/261/dht-blockers/</guid>
		<description><![CDATA[Q: Are there DHT blockers that are sold in the pharmacy over the counter?
A: The only effective DHT blockers are finasteride (Propecia, Proscar) and dutasteride (Avodart).
These medications require a doctor&#8217;s prescription and are not sold OTC. Nizoral is a topical shampoo for seborrhea (a type of dandruff) that is sold over the counter, but it [...]]]></description>
			<content:encoded><![CDATA[<p><strong>Q:</strong> Are there DHT blockers that are sold in the pharmacy over the counter?</p>
<p><strong>A:</strong> The only effective DHT blockers are finasteride (Propecia, Proscar) and dutasteride (Avodart).</p>
<p>These medications require a doctor&#8217;s prescription and are not sold OTC. Nizoral is a topical shampoo for seborrhea (a type of dandruff) that is sold over the counter, but it is not effective in treating hair loss.</p>
]]></content:encoded>
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		<item>
		<title>Do You Recommend Avodart (Dutasteride) Hair Loss Medication?</title>
		<link>http://www.bernsteinmedical.com/hairtransplantblog/recommending-avodart/</link>
		<comments>http://www.bernsteinmedical.com/hairtransplantblog/recommending-avodart/#comments</comments>
		<pubDate>Mon, 25 Feb 2008 07:19:00 +0000</pubDate>
		<dc:creator>Robert M. Bernstein M.D.</dc:creator>
				<category><![CDATA[Drugs (Medications)]]></category>
		<category><![CDATA[Alpha-type 1 Receptors in the Brain]]></category>
		<category><![CDATA[Avodart]]></category>
		<category><![CDATA[DHT]]></category>
		<category><![CDATA[DHT Blockers]]></category>
		<category><![CDATA[Dutasteride]]></category>
		<category><![CDATA[Finasteride]]></category>
		<category><![CDATA[Hair Loss Medication]]></category>
		<category><![CDATA[Hair Loss Medication Dosage]]></category>
		<category><![CDATA[Medication Side Effects]]></category>
		<category><![CDATA[Miniaturization]]></category>
		<category><![CDATA[Propecia]]></category>
		<category><![CDATA[Prostate]]></category>
		<category><![CDATA[Prostate Disease]]></category>
		<category><![CDATA[Sex Drive]]></category>
		<category><![CDATA[Sexual Side Effects]]></category>
		<category><![CDATA[Sperm Count]]></category>

		<guid isPermaLink="false">http://www.bernsteinmedical.com/dev/newblog/252/recommending-avodart/</guid>
		<description><![CDATA[Q: I heard that there is a new drug on the market called Avodart for prostate enlargement which might help with hair loss as it blocks the conversion of testosterone to DHT better than Finasteride and is more effective than Propecia. Do you recommend taking it and if so what is the dose?
A: I am [...]]]></description>
			<content:encoded><![CDATA[<p><strong>Q:</strong> I heard that there is a new drug on the market called Avodart for prostate enlargement which might help with hair loss as it blocks the conversion of testosterone to DHT better than Finasteride and is more effective than Propecia. Do you recommend taking it and if so what is the dose?</p>
<p><strong>A:</strong> I am currently not recommending that patients take Dutasteride for hair loss, although it is more effective than Propecia, finasteride 1mg. (Dutasteride 0.5, the dose generally used for hair loss, seems to be slightly more effective than finasteride 5m in reversing miniaturization.)</p>
<p>The reasons that I am hesitant to prescribe it at present are outlined in the Hair Transplant Blog question <a href="http://www.bernsteinmedical.com/hairtransplantblog/is-avodart-safe/128/">Is Avodart Safe?</a></p>
<p>In addition to the reasons that I listed in that response, I would also consider that: Dutasteride, unlike finasteride, decreases sperm counts, it can result in persistent decreased sex drive and the incidence is greater than with finasteride. Finally there are a significant number of alpha-type 1 receptors in brain, those affected by dutasteride, but not finasteride.</p>
<p>However, since Dutasteride is approved for older men with prostatic disease, using it for hair loss in this age group (usually in a lower dose) is reasonable.</p>
]]></content:encoded>
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		</item>
		<item>
		<title>Can Avodart Hair Loss Medication Cause Shedding?</title>
		<link>http://www.bernsteinmedical.com/hairtransplantblog/shedding-on-avodart/</link>
		<comments>http://www.bernsteinmedical.com/hairtransplantblog/shedding-on-avodart/#comments</comments>
		<pubDate>Mon, 30 Apr 2007 03:19:00 +0000</pubDate>
		<dc:creator>Robert M. Bernstein M.D.</dc:creator>
				<category><![CDATA[Drugs (Medications)]]></category>
		<category><![CDATA[Avodart]]></category>
		<category><![CDATA[Dutasteride]]></category>
		<category><![CDATA[Early Hair Loss]]></category>
		<category><![CDATA[Finasteride]]></category>
		<category><![CDATA[Hair Loss Medication]]></category>
		<category><![CDATA[Propecia]]></category>
		<category><![CDATA[Shedding]]></category>
		<category><![CDATA[Shedding at Start of Treatment with Medication]]></category>
		<category><![CDATA[Telogen Effluvium]]></category>

		<guid isPermaLink="false">http://www.bernsteinmedical.com/dev/newblog/214/shedding-on-avodart/</guid>
		<description><![CDATA[Q: I&#8217;m male, early thirties and in the early stages of hair loss, too early for hair transplants. I am experiencing extreme shedding. I took Avodart for 6 weeks, but because of the shedding I stopped. Now, it still continues as strong as ever. I&#8217;ve been losing about 200 hairs every day in the shower. [...]]]></description>
			<content:encoded><![CDATA[<p><strong>Q:</strong> I&#8217;m male, early thirties and in the early stages of hair loss, too early for hair transplants. I am experiencing extreme shedding. I took Avodart for 6 weeks, but because of the shedding I stopped. Now, it still continues as strong as ever. I&#8217;ve been losing about 200 hairs every day in the shower. 3 months ago I had so much more hair, what is going on? I heard that shedding can happen, but not like this. Could this have caused telogen effluvium, or something else?</p>
<p><strong>A:</strong> Since Avodart (dutasteride) is a more potent medication than Propecia (finasteride), the shedding (telogen effluvium) may be more dramatic. If you have made a decision to use Avodart, then you need to tolerate this short-term effect. It should subside within the first 6 months on the drug.</p>
]]></content:encoded>
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		</item>
		<item>
		<title>Should One Use Multiple Hair Loss Medications, Such as Both Avodart and Propecia?</title>
		<link>http://www.bernsteinmedical.com/hairtransplantblog/avodart-and-propecia/</link>
		<comments>http://www.bernsteinmedical.com/hairtransplantblog/avodart-and-propecia/#comments</comments>
		<pubDate>Fri, 09 Feb 2007 09:15:48 +0000</pubDate>
		<dc:creator>Robert M. Bernstein M.D.</dc:creator>
				<category><![CDATA[Drugs (Medications)]]></category>
		<category><![CDATA[Avodart]]></category>
		<category><![CDATA[DHT]]></category>
		<category><![CDATA[DHT Blockers]]></category>
		<category><![CDATA[Dutasteride]]></category>
		<category><![CDATA[Finasteride]]></category>
		<category><![CDATA[Hair loss in Men]]></category>
		<category><![CDATA[Hair Loss Medication]]></category>
		<category><![CDATA[Hair Loss Medication Dosage]]></category>
		<category><![CDATA[Multiple Medications]]></category>
		<category><![CDATA[Propecia]]></category>
		<category><![CDATA[Testosterone]]></category>

		<guid isPermaLink="false">http://www.bernsteinmedical.com/dev/newblog/147/avodart-and-propecia/</guid>
		<description><![CDATA[Q: I&#8217;m 52 years old and have been taking Propecia (finasteride) for two years. It seems to maintain the status quo with no apparent regrowth. I am considering adding a dose of Avodart (dutasteride) once a week in conjunction with the daily Propecia. My question is twofold: (1) Since dutasteride blocks production of both enzymes [...]]]></description>
			<content:encoded><![CDATA[<p><strong>Q:</strong> I&#8217;m 52 years old and have been taking Propecia (finasteride) for two years. It seems to maintain the status quo with no apparent regrowth. I am considering adding a dose of Avodart (dutasteride) once a week in conjunction with the daily Propecia. My question is twofold: (1) Since dutasteride blocks production of both enzymes (type I and II) that produce DHT from testosterone, is it redundant to take the finasteride that only blocks the type I enzyme?</p>
<p><strong>A: </strong>It is redundant to take both.</p>
<p>However, you may not be taking the optimal dose of dutasteride which seems to be at least 0.5mg a day for hair loss.</p>
]]></content:encoded>
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