5-Alpha Reductase

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Are There Any Lab Studies Proving that Saw Palmetto Helps Prevent Hair Loss?

August 19th, 2011

Q: Have there been any lab studies proving that Saw Palmetto works to prevent hair loss?

A: There have been no verifiable clinical studies that show saw palmetto can stop hair loss or cause hair to re-grow. There have been some preliminary tests showing that saw palmetto may be able to inhibit 5-alpha-reductase, but its usefulness for androgenetic hair loss has not been documented in controlled studies.




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Posted by Robert M. Bernstein M.D. at 6:12 pm

What is Saw Palmetto and does it Prevent Hair Loss?

August 15th, 2011

Q: What is Saw Palmetto?

A: Saw Palmetto is a dwarf palm plant native to North America. The active ingredients can be found in the plant’s brown-black berries. It’s proposed that it blocks the enzyme 5-alpha-reductase that converts testosterone to dihydrotestosterone (DHT). There is little scientific evidence that Saw Palmetto is actually effective for hair loss.




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Posted by Robert M. Bernstein M.D. at 5:24 am

Can Body Hair Transplant be Negatively Affected by Finasteride?

March 4th, 2011

After trading anecdotes with fellow hair loss physicians about how finasteride can reduce body hair in some patients, Dr. Sharon A. Keene asked whether finasteride might have a negative affect on patients who have body hair transplant (BHT) procedures. While the current research is inconclusive, her review sheds light on how to avoid any possible negative impact that finasteride might have on patients who have body hair transplant procedures.




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Posted by Ethan at Bernstein Medical at 6:00 am

Could Finasteride (Propecia) Remove Unwanted Body Hair?

August 23rd, 2010

Q: I’m concerned that finasteride might result in unwanted body hair on the arms, back, etc. Is there any truth to this? My thinking is that since finasteride blocks the enzyme 5 alpha-reductase which converts testosterone to its more active form, DHT (dihydrotestosterone), is it possible that it might actually have some effectiveness in ameliorating unwanted hair?

A: Yes, finasteride does have some ability to decrease body hair, since growth of body hair is stimulated by DHT. However, the effects of finasteride are mild and not observed by everyone, so if you have unwanted body hair you will probably need some other means to remove it such as waxing, laser hair removal or electrolysis. The important thing is that finasteride doesn’t increase body hair.




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Posted by Robert M. Bernstein M.D. at 7:38 am

Is Hair Loss Treatment with Avodart Safe?

September 1st, 2006

Q: My friend is taking Avodart, he bought it over the internet. Is it safe to take? A: Avodart (dutasteride 0.5mg) was approved by the FDA for the treatment of prostate enlargement in men in 2002. Avodart has not been approved for the treatment of androgenetic hair loss, although physicians can use an approved medication [...]




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Posted by Robert M. Bernstein M.D. at 5:30 am


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