Can Hair Loss Treatment with Propecia Affect Prostate Specific Antigen (PSA) Level?

February 13th, 2007

Q: I have been on Propecia for approximately 5 years. What does Propecia do to your PSA level, lower it or make it higher? Also, what would you consider a normal level while on Propecia?

A: Finasteride 1mg a day lowers your PSA around 50%. Therefore, when patients are taking finasteride, the PSA reading should be doubled.

Finasteride does not appear to decrease the sensitivity of the PSA test to detect prostate cancer – its main purpose.

PSA levels vary by age and by lab so I would check with your internist/urologist to evaluate your specific level.

In very general terms, for adults, it is ideal to have a PSA < 1.0 off Propecia and < 0.5 on it, but higher levels can also be fine.

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Posted by Robert M. Bernstein M.D. on February 13th, 2007 at 10:17 am


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